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Inhibition of inducible heat shock protein-70 (hsp72) enhances bortezomib-induced cell death in human bladder cancer cells.

The proteasome inhibitor bortezomib (Velcade) is a promising new agent for bladder cancer therapy, but inducible cytoprotective mechanisms may limit its potential efficacy. We used whole genome mRNA expression profiling to study the effects of bortezomib on stress-induced gene expression in a panel...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Wei Qi, Matthew C White, Woonyoung Choi, Charles Guo, Colin Dinney, David J McConkey, Arlene Siefker-Radtke
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2013-01-01
Цуврал:PLoS ONE
Онлайн хандалт:http://europepmc.org/articles/PMC3715471?pdf=render
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