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Fibroblast growth factor receptors-1 and -3 play distinct roles in the regulation of bladder cancer growth and metastasis: implications for therapeutic targeting.

Fibroblast growth factor receptors (FGFRs) are activated by mutation and overexpressed in bladder cancers (BCs), and FGFR inhibitors are currently being evaluated in clinical trials in BC patients. However, BC cells display marked heterogeneity in their responses to FGFR inhibitors, and the biologic...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Tiewei Cheng, Beat Roth, Woonyoung Choi, Peter C Black, Colin Dinney, David J McConkey
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2013-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC3582560?pdf=render
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