Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.

Bladder cancer (BLCA) genomic profiling has identified molecular subtypes with distinct clinical characteristics and variable sensitivities to frontline therapy. BLCAs can be categorized into luminal or basal subtypes based on their gene expression. We comprehensively characterized nine human BLCA c...

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Detalhes bibliográficos

Principais autores:	Sharada Mokkapati, Ganiraju Manyam, Alexis R. Steinmetz, Côme Tholomier, Alberto Martini, Woonyoung Choi, Bogdon Czerniak, Byron H Lee, Colin P Dinney, David J McConkey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-02-01
coleção:	Translational Oncology
Assuntos:	Bladder cancer Molecular subtypes of bladder cancer Transcriptomic classifier Luminal Basal
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1936523324003954
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