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The Evolution of Nadofaragene Firadenovec: A Review and the Path Forward

BACKGROUND: The intravesical gene therapy nadofaragene firadenovec (rAd-IFNα/Syn3) was FDA approved in 2022 for non-muscle invasive bladder cancer (NMIBC) unresponsive to frontline treatment with BCG, and the first gene therapy developed for bladder cancer. This non-replicating recombinant adenoviru...

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Principais autores: Alexis R. Steinmetz, Sharada Mokkapati, David McConkey, Colin P. Dinney
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publishing 2024-06-01
Series:Bladder Cancer
Acceso en liña:https://doi.org/10.3233/BLC-230083
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