Código QR

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

ABSTRACT The use of chimeric antigen receptor (CAR) T‐cell therapy for T‐cell malignancies is limited by fratricide, antigen‐escape, lack of functional endurance and adverse events such as multilineage cytopenia. To address these limitations, we developed a simple single‐step CD7‐depletion process f...

ver descrição completa

Na minha lista:
Principais autores: Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2026-06-01
Colecção:Advanced Science
Assuntos:
cancer immunotherapy
CAR T‐cell therapy
dual‐targeted therapy
hematological disease
t‐cell malignancies
Acesso em linha:https://doi.org/10.1002/advs.202521443
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados