Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
ABSTRACT The use of chimeric antigen receptor (CAR) T‐cell therapy for T‐cell malignancies is limited by fratricide, antigen‐escape, lack of functional endurance and adverse events such as multilineage cytopenia. To address these limitations, we developed a simple single‐step CD7‐depletion process f...
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| Автори: | , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Wiley
2026-06-01
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| Серія: | Advanced Science |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1002/advs.202521443 |
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