Rotational restriction of nascent peptides as an essential element of co-translational protein folding: possible molecular players and structural consequences

Abstract Background A basic tenet of protein science is that all information about the spatial structure of proteins is present in their sequences. Nonetheless, many proteins fail to attain native structure upon experimental denaturation and refolding in vitro, raising the question of the specific r...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Irina Sorokina, Arcady Mushegian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-05-01
coleção:	Biology Direct
Assuntos:	Protein folding Protein backbone twist Protein backbone torsion Peptide backbone twist Peptide backbone torsion Co-translational protein folding
Acesso em linha:	http://link.springer.com/article/10.1186/s13062-017-0186-1
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!