Enhancing co-translational folding of heterologous protein by deleting non-essential ribosomal proteins in Pichia pastoris

Abstract Background Translational regulation played an important role in the correct folding of heterologous proteins to form bioactive conformations during biogenesis. Translational pausing coordinates protein translation and co-translational folding. Decelerating translation elongation speed has b...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xihao Liao, Jing Zhao, Shuli Liang, Jingjie Jin, Cheng Li, Ruiming Xiao, Lu Li, Meijin Guo, Gong Zhang, Ying Lin
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-02-01
Цуврал:	Biotechnology for Biofuels
Нөхцлүүд:	Heterologous protein Pichia pastoris Ribosomal protein Translation Co-translational folding
Онлайн хандалт:	http://link.springer.com/article/10.1186/s13068-019-1377-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!