IL-27 alters inflammatory cytokine expression and limits protective immunity against Mycobacterium tuberculosis in a neonatal BCG vaccination model

BackgroundEfforts to control tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis (Mtb), have been hampered by the immense variability in protection from BCG vaccination. While BCG protects young children from some forms of TB disease, long-term protection against pulmonary disease i...

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Главные авторы:	Shelby D. Bradford, Kenneth J. Ryan, Ashley M. Divens, Jessica M. Povroznik, Sunilkanth Bonigala, Cory M. Robinson
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2024-02-01
Серии:	Frontiers in Immunology
Предметы:	interleukin-27 neonate BCG tuberculosis vaccine vaccination
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1217098/full
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