Synthesis, Biological Evaluation, and In Silico Modeling of <i>N</i>-Substituted Quinoxaline-2-Carboxamides

Despite the established treatment regimens, tuberculosis remains an alarming threat to public health according to WHO. Novel agents are needed to overcome the increasing rate of resistance and perhaps achieve eradication. As part of our long-term research on pyrazine derived compounds, we prepared a...

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Autors principals:	Ghada Bouz, Sarah Bouz, Ondřej Janďourek, Klára Konečná, Pavel Bárta, Jarmila Vinšová, Martin Doležal, Jan Zitko
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-08-01
Col·lecció:	Pharmaceuticals
Matèries:	antimycobacterial cytotoxicity molecular docking <i>Mycobacterium tuberculosis</i> pyrazinamide quinoxaline
Accés en línia:	https://www.mdpi.com/1424-8247/14/8/768
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