Design, Synthesis, and Biological Evaluation of New Benzoxaborole Derivatives as Potential Antimycobacterial Agents

The current study is focused on the combination of pyrazinamide with 6-aminobenzo[c][1,2]oxaborol-1(3<i>H</i>)-ol, which is a crucial pharmacophore of several antimicrobial agents. The use of benzoxaborole moiety could afford the formation of a spiro adduct between benzoxaborole moiety and 3'-termin...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Petr Šlechta, Ondřej Jand’ourek, Klára Konečná, Pavla Paterová, Pavel Bárta, Vladimír Kubíček, Martin Doležal, Marta Kučerová-Chlupáčová
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2022-11-01
Sarja:	Medical Sciences Forum
Aiheet:	benzoxaborole Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Ra HepG2 cancer cell line leucyl-tRNA synthetase
Linkit:	https://www.mdpi.com/2673-9992/14/1/133
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