Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology

Mitochondrial permeability transition (MPT) is the sudden loss in the permeability of the inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic forces, MPT is paralleled by a massive influx of water into the mitochondrial matrix, eventually leading to the structural coll...

Полное описание

Библиографические подробности

Главные авторы:	Massimo Bonora, Simone Patergnani, Daniela Ramaccini, Giampaolo Morciano, Gaia Pedriali, Asrat Endrias Kahsay, Esmaa Bouhamida, Carlotta Giorgi, Mariusz R. Wieckowski, Paolo Pinton
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2020-07-01
Серии:	Biomolecules
Предметы:	mitochondrial permeability transition apoptosis necrosis ischemia/reperfusion cancer neurodegeneration
Online-ссылка:	https://www.mdpi.com/2218-273X/10/7/998
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