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Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology

Mitochondrial permeability transition (MPT) is the sudden loss in the permeability of the inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic forces, MPT is paralleled by a massive influx of water into the mitochondrial matrix, eventually leading to the structural coll...

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Kaydedildi:
Asıl Yazarlar: Massimo Bonora, Simone Patergnani, Daniela Ramaccini, Giampaolo Morciano, Gaia Pedriali, Asrat Endrias Kahsay, Esmaa Bouhamida, Carlotta Giorgi, Mariusz R. Wieckowski, Paolo Pinton
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-07-01
Seri Bilgileri:Biomolecules
Konular:
mitochondrial permeability transition
apoptosis
necrosis
ischemia/reperfusion
cancer
neurodegeneration
Online Erişim:https://www.mdpi.com/2218-273X/10/7/998
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