ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia
Phosphatidylserine is localized exclusively to the inner leaflet of the membrane lipid bilayer of most cells, including erythrocytes. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized phosphatidylserine is a phagocytic signal for splenic macr...
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| Huvudupphov: | , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Ferrata Storti Foundation
2016-05-01
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| Serie: | Haematologica |
| Länkar: | https://haematologica.org/article/view/7704 |
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