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ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia

Phosphatidylserine is localized exclusively to the inner leaflet of the membrane lipid bilayer of most cells, including erythrocytes. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized phosphatidylserine is a phagocytic signal for splenic macr...

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Auteurs principaux: Nobuto Arashiki, Yuichi Takakuwa, Narla Mohandas, John Hale, Kenichi Yoshida, Hiromi Ogura, Taiju Utsugisawa, Shouichi Ohga, Satoru Miyano, Seishi Ogawa, Seiji Kojima, Hitoshi Kanno
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2016-05-01
Collection:Haematologica
Accès en ligne:https://haematologica.org/article/view/7704
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