Discontiguous recurrences of IDH-wildtype glioblastoma share a common origin with the initial tumor and are frequently hypermutated

Abstract Glioblastoma is the deadliest primary brain tumor, largely due to inevitable recurrence of the disease after treatment. While most recurrences are local, patients rarely present with a new discontiguous focus of glioblastoma. Little is currently known about the genetic profile of discontigu...

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主要な著者:	Malcolm F. McDonald, Sricharan Gopakumar, Tareq A. Juratli, Ilker Y. Eyüpoglu, Ganesh Rao, Jacob J. Mandel, Ali Jalali
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-01-01
シリーズ:	Acta Neuropathologica Communications
主題:	IDH WT glioma Glioblastoma recurrence Multicentric Discontiguous Hypermutation
オンライン･アクセス:	https://doi.org/10.1186/s40478-024-01900-1
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