Functional Expression in <em>Es</em><em>c</em><em>herichia coli</em> of the Disulfide-Rich Sea Anemone Peptide APETx2, a Potent Blocker of Acid-Sensing Ion Channel 3

Acid-sensing ion channels (ASICs) are proton-gated sodium channels present in the central and peripheral nervous system of chordates. ASIC3 is highly expressed in sensory neurons and plays an important role in inflammatory and ischemic pain. Thus, specific inhibitors of ASIC3 have the potential to b...

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Үндсэн зохиолчид:	Glenn F. King, Mehdi Mobli, Raveendra Anangi, Lachlan D. Rash
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2012-07-01
Цуврал:	Marine Drugs
Нөхцлүүд:	ASIC3 APETx2 heterologous expression NMR <em>E. coli</em>
Онлайн хандалт:	http://www.mdpi.com/1660-3397/10/7/1605
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!