Functional Expression in <em>Es</em><em>c</em><em>herichia coli</em> of the Disulfide-Rich Sea Anemone Peptide APETx2, a Potent Blocker of Acid-Sensing Ion Channel 3
Acid-sensing ion channels (ASICs) are proton-gated sodium channels present in the central and peripheral nervous system of chordates. ASIC3 is highly expressed in sensory neurons and plays an important role in inflammatory and ischemic pain. Thus, specific inhibitors of ASIC3 have the potential to b...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MDPI AG
2012-07-01
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| Seria: | Marine Drugs |
| Hasła przedmiotowe: | |
| Dostęp online: | http://www.mdpi.com/1660-3397/10/7/1605 |
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