Functional Expression in <em>Es</em><em>c</em><em>herichia coli</em> of the Disulfide-Rich Sea Anemone Peptide APETx2, a Potent Blocker of Acid-Sensing Ion Channel 3

Acid-sensing ion channels (ASICs) are proton-gated sodium channels present in the central and peripheral nervous system of chordates. ASIC3 is highly expressed in sensory neurons and plays an important role in inflammatory and ischemic pain. Thus, specific inhibitors of ASIC3 have the potential to b...

Полное описание

Библиографические подробности

Главные авторы:	Glenn F. King, Mehdi Mobli, Raveendra Anangi, Lachlan D. Rash
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2012-07-01
Серии:	Marine Drugs
Предметы:	ASIC3 APETx2 heterologous expression NMR <em>E. coli</em>
Online-ссылка:	http://www.mdpi.com/1660-3397/10/7/1605
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!