Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response.
Insulin-secreting β-cells are functionally heterogeneous. Whether there exist cells driving the first-phase calcium response in individual islets, has not been examined. We examine "first responder" cells, defined by the earliest [Ca2+] response during first-phase [Ca2+] elevation, distinct from pre...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2022-09-01
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| Seri Bilgileri: | PLoS Biology |
| Online Erişim: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001761&type=printable |
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