AlphaFold-Guided Semi-Rational Engineering of an (<i>R</i>)-Amine Transaminase for Green Synthesis of Chiral Amines
Chiral amines are vital structural motifs in pharmaceuticals and agrochemicals, where enantiomeric purity governs bioactivity and environmental behavior. We identified a novel (<i>R</i>)-selective amine transaminase (MwoAT) from <i>Mycobacterium</i> sp. via genome mining, which exhibits activity tow...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2025-10-01
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| Серія: | Biomolecules |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2218-273X/15/10/1435 |
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