Fast-tracking antibody maturation using a B cell-based display system
Affinity maturation, an essential component of antibody engineering, is crucial for developing therapeutic antibodies. Cell display system coupled with somatic hypermutation (SHM) initiated by activation-induced cytidine deaminase (AID) is a commonly used technique for affinity maturation. AID intro...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis Group
2022-12-01
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| Schriftenreihe: | mAbs |
| Schlagworte: | |
| Online-Zugang: | https://www.tandfonline.com/doi/10.1080/19420862.2022.2122275 |
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