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Trans ε-Viniferin Decreases Amyloid Deposits With Greater Efficiency Than Resveratrol in an Alzheimer’s Mouse Model

In a previous study, we showed that viniferin decreased amyloid deposits and reduced neuroinflammation in APPswePS1dE9 transgenic mice between 3 and 6 months of age. In the present study, wild type and APPswePS1dE9 transgenic mice were treated from 7 to 11 or from 3 to 12 months by a weekly intraper...

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Principais autores: Aline Freyssin, Agnès Rioux Bilan, Bernard Fauconneau, Laurent Galineau, Sophie Serrière, Clovis Tauber, Flavie Perrin, Jérôme Guillard, Sylvie Chalon, Guylène Page
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-01-01
coleção:Frontiers in Neuroscience
Assuntos:
Alzheimer’s disease
viniferin
resveratrol
PET imaging
amyloid deposits
memory decline
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnins.2021.803927/full
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