G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound.

Anti-mitotic therapies have been considered a hallmark in strategies against abnormally proliferating cells. Focusing on the extensively studied family of thiosemicarbazone (TSC) compounds, we have previously identified 4,4'-dimethoxybenzophenone thiosemicarbazone (T44Bf) as a promising pharmacologi...

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Principais autores:	Maia Cabrera, Natalia Gomez, Federico Remes Lenicov, Emiliana Echeverría, Carina Shayo, Albertina Moglioni, Natalia Fernández, Carlos Davio
格式:	Artigo
语言:	Inglês
出版:	Public Library of Science (PLoS) 2015-01-01
丛编:	PLoS ONE
在线阅读:	http://europepmc.org/articles/PMC4567328?pdf=render
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