Activity of DNA- and RNA-Guided Prokaryotic Argonautes in Human Mitochondria
Precise manipulation of mitochondrial DNA (mtDNA) by CRISPR-Cas systems remains challenging, largely due to inefficient import of guide RNAs, motivating the exploration of alternative programmable nucleases. Here, we show that prokaryotic Argonaute nucleases (pAgos) of various classes can be efficie...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2026-06-01
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| Col·lecció: | Cells |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/2073-4409/15/12/1129 |
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