SAP-expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis

IntroductionT follicular (TFH) and peripheral helper (TPH) cells have been increasingly recognized as a pathogenic subset of CD4 T cells in systemic lupus erythematosus (SLE). The SLAM Associated Protein (SAP) regulates TFH and TPH function by binding to the co-stimulatory signaling lymphocyte activ...

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Autors principals:	Yevgeniya Gartshteyn, Laura Geraldino-Pardilla, Leila Khalili, Shoiab Bukhari, Shalom Lerrer, Robert J. Winchester, Anca D. Askanase, Adam Mor
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-03-01
Col·lecció:	Frontiers in Immunology
Matèries:	systemic lupus lupus nephritis T peripheral helper cells T follicular helper cells SLAM SAP
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1327437/full
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