KLRG1 expression induces functional exhaustion of NK cells in colorectal cancer patients

Abstract Background Natural killer (NK) cells are a subset of innate lymphoid cells that possess cytotoxic properties, playing a pivotal role in immune surveillance against tumor cells. However, it remains unclear whether there are any alterations in the quantity and functional status of NK cells in...

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Detalhes bibliográficos

Principais autores:	Cairui Xu, Kangli Cao, Along Ma, Meijuan Zheng, Yuanhong Xu, Ling Tang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2025-05-01
coleção:	Cancer Immunology, Immunotherapy
Assuntos:	Colorectal cancer NK cells KLRG1 Dysfunction Immunotherapy
Acesso em linha:	https://doi.org/10.1007/s00262-025-04059-3
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