Spatially microdissected profiling of tonsillar germinal centers reveals a KLRG1-enriched immune signature in IgA nephropathy

BackgroundGeographic variability in the clinical efficacy of tonsillectomy for immunoglobulin A nephropathy (IgAN) suggests population-level differences in mucosal immune architecture. However, the molecular features of the tonsillar germinal center (GC) microenvironment—the central site for IgA cla...

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Váldodahkkit:	Mayuko Kawabe, Izumi Yamamoto, Yutaro Ohki, Ayaka Hayashi, Go Kanzaki, Kei Matsumoto, Hiroyuki Ueda, Keita Hirano, Nobuo Tsuboi, Takashi Yokoo
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2026-05-01
Ráidu:	Frontiers in Immunology
Fáttát:	germinal center IgA nephropathy KLRG1 mucosal immunity tonsil
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1750300/full
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