Loss of chondroitin sulfate proteoglycan sulfation allows delayed sympathetic reinnervation after cardiac ischemia–reperfusion

Abstract Sympathetic nerve loss in the heart predicts the risk of ventricular arrhythmias after myocardial infarction (MI) in patients. Sympathetic denervation after cardiac ischemia–reperfusion is sustained by matrix components chondroitin sulfate proteoglycans (CSPGs) in the cardiac scar. We showe...

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Autores principales:	Matthew R. Blake, Diana C. Parrish, Melanie A. Staffenson, Morgan A. Johnson, William R. Woodward, Beth A. Habecker
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2023-05-01
Colección:	Physiological Reports
Materias:	extracellular matrix ischemia–reperfusion sympathetic nervous system
Acceso en línea:	https://doi.org/10.14814/phy2.15702
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