Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

Abstract Background DNA methylation is an important epigenetic mechanism involved in gene regulation, with alterations in DNA methylation in the nuclear genome being linked to numerous complex diseases. Mitochondrial DNA methylation is a phenomenon that is receiving ever-increasing interest, particu...

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Auteurs principaux:	Matthew Devall, Rebecca G. Smith, Aaron Jeffries, Eilis Hannon, Matthew N. Davies, Leonard Schalkwyk, Jonathan Mill, Michael Weedon, Katie Lunnon
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2017-05-01
Collection:	Clinical Epigenetics
Sujets:	5-mC 5-Methylcytosine Blood Brain DNA methylation Epigenetics
Accès en ligne:	http://link.springer.com/article/10.1186/s13148-017-0337-3
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