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Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

Abstract Background DNA methylation is an important epigenetic mechanism involved in gene regulation, with alterations in DNA methylation in the nuclear genome being linked to numerous complex diseases. Mitochondrial DNA methylation is a phenomenon that is receiving ever-increasing interest, particu...

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Kaydedildi:
Asıl Yazarlar: Matthew Devall, Rebecca G. Smith, Aaron Jeffries, Eilis Hannon, Matthew N. Davies, Leonard Schalkwyk, Jonathan Mill, Michael Weedon, Katie Lunnon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2017-05-01
Seri Bilgileri:Clinical Epigenetics
Konular:
5-mC
5-Methylcytosine
Blood
Brain
DNA methylation
Epigenetics
Online Erişim:http://link.springer.com/article/10.1186/s13148-017-0337-3
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