Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

Abstract Background DNA methylation is an important epigenetic mechanism involved in gene regulation, with alterations in DNA methylation in the nuclear genome being linked to numerous complex diseases. Mitochondrial DNA methylation is a phenomenon that is receiving ever-increasing interest, particu...

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Autors principals:	Matthew Devall, Rebecca G. Smith, Aaron Jeffries, Eilis Hannon, Matthew N. Davies, Leonard Schalkwyk, Jonathan Mill, Michael Weedon, Katie Lunnon
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2017-05-01
Col·lecció:	Clinical Epigenetics
Matèries:	5-mC 5-Methylcytosine Blood Brain DNA methylation Epigenetics
Accés en línia:	http://link.springer.com/article/10.1186/s13148-017-0337-3
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