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Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters

The emergence of new protein functions is crucial for the evolution of organisms. This process has been extensively researched for soluble enzymes, but it is largely unexplored for membrane transporters, even though the ability to acquire new nutrients from a changing environment requires evolvabili...

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Bibliografiset tiedot
Päätekijät: Foteini Karapanagioti, Úlfur Águst Atlason, Dirk J Slotboom, Bert Poolman, Sebastian Obermaier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications Ltd 2024-06-01
Sarja:eLife
Aiheet:
Linkit:https://elifesciences.org/articles/93971
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