Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters

The emergence of new protein functions is crucial for the evolution of organisms. This process has been extensively researched for soluble enzymes, but it is largely unexplored for membrane transporters, even though the ability to acquire new nutrients from a changing environment requires evolvabili...

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Autors principals:	Foteini Karapanagioti, Úlfur Águst Atlason, Dirk J Slotboom, Bert Poolman, Sebastian Obermaier
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2024-06-01
Col·lecció:	eLife
Matèries:	amino acid transport experimental evolution adaptive mutations yeast amino acid-polyamine-organocation transport family
Accés en línia:	https://elifesciences.org/articles/93971
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