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Analysis of translatomic changes in the Ubqln2P497S model of ALS reveals that motor neurons express muscle-associated genes in non-disease states

IntroductionAmyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressively worsening motor symptoms that lead to eventual fatal paralysis. The number of gene mutations associated with ALS have increased dramatically in recent years, suggesting heterogen...

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Principais autores: Wesley M. Stansberry, Natalie C. Fiur, Melissa M. Robins, Brian A. Pierchala
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-11-01
coleção:Frontiers in Neurology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fneur.2024.1491415/full
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