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Regulatory role of serine 59 in the oligomeric dynamics and chaperone function of αB-crystallin

Abstract We previously demonstrated that deletion of the 54FLRAPSW61 sequence, containing the key phosphorylation site serine 59 (S59), resulted in a two-fold reduction in oligomeric mass and a ten-fold enhancement of αB-crystallin’s chaperone activity. This study examined whether targeted deletion...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tenzin Tender, Puttur Santhoshkumar, Leena Suleiman, Md Rejaul Hoq, K. Krishna Sharma
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-10-01
Saila:Scientific Reports
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-21161-9
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