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mTORC1 and mTORC2 differentially promote natural killer cell development

Natural killer (NK) cells are innate lymphoid cells that are essential for innate and adaptive immunity. Mechanistic target of rapamycin (mTOR) is critical for NK cell development; however, the independent roles of mTORC1 or mTORC2 in regulating this process remain unknown. Ncr1iCre-mediated deletio...

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Detalhes bibliográficos
Principais autores: Chao Yang, Shirng-Wern Tsaih, Angela Lemke, Michael J Flister, Monica S Thakar, Subramaniam Malarkannan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2018-05-01
Colecção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/35619
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