In Vitro Evaluation of Drug–Drug Interaction Potential of Epetraborole, a Novel Bacterial Leucyl-tRNA Synthetase Inhibitor

Epetraborole (EBO) is a boron-containing inhibitor of bacterial leucyl-tRNA synthetase, with potent activity against nontuberculous mycobacteria (NTM) and Gram-negative bacteria, including <i>Burkholderia pseudomallei</i>. EBO is being developed for the treatment of NTM lung disease and melioidosis,...

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Hlavní autoři:	Afshin Shafiee, Sanjay Chanda
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-01-01
Edice:	Pharmaceuticals
Témata:	epetraborole drug–drug interaction bacterial leucyl-tRNA synthetase <i>Mycobacterium avium</i> complex melioidosis in vitro studies
On-line přístup:	https://www.mdpi.com/1424-8247/17/1/120
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