In Vitro Evaluation of Drug–Drug Interaction Potential of Epetraborole, a Novel Bacterial Leucyl-tRNA Synthetase Inhibitor

Epetraborole (EBO) is a boron-containing inhibitor of bacterial leucyl-tRNA synthetase, with potent activity against nontuberculous mycobacteria (NTM) and Gram-negative bacteria, including <i>Burkholderia pseudomallei</i>. EBO is being developed for the treatment of NTM lung disease and melioidosis,...

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Bibliographic Details

Main Authors:	Afshin Shafiee, Sanjay Chanda
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2024-01-01
Series:	Pharmaceuticals
Subjects:	epetraborole drug–drug interaction bacterial leucyl-tRNA synthetase <i>Mycobacterium avium</i> complex melioidosis in vitro studies
Online Access:	https://www.mdpi.com/1424-8247/17/1/120
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