Targeting Sigma-1 and Sigma-2 Receptors in Neuropathic Pain: Pharmacology, Ligand Development, and Translational Progress
Background: Neuropathic pain remains a major unmet clinical challenge. Growing evidence identifies sigma receptors (σRs) as pivotal intracellular modulators of maladaptive stress signaling, positioning them as promising non-opioid targets for chronic pain management. Notably, despite the pleiotropic...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI AG
2026-03-01
|
| Colección: | Brain Sciences |
| Materias: | |
| Acceso en línea: | https://www.mdpi.com/2076-3425/16/4/371 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|