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Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain

Sigma receptors modulate nociception, offering a potential therapeutic target to treat pain, but relatively little is known regarding the role of sigma-2 receptors (S2R) in nociception. The purpose of this study was to investigate the in vivo analgesic and anti-allodynic activity and liabilities of...

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Váldodahkkit: Lisa L. Wilson, Amy R. Alleyne, Shainnel O. Eans, Thomas J. Cirino, Heather M. Stacy, Marco Mottinelli, Sebastiano Intagliata, Christopher R. McCurdy, Jay P. McLaughlin
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2022-06-01
Ráidu:Molecules
Fáttát:
Liŋkkat:https://www.mdpi.com/1420-3049/27/11/3617
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