Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.
Vision impairment places a serious burden on the aging society, affecting the lives of millions of people. Many retinal diseases are of genetic origin, of which over 50% are due to mutations in cilia-associated genes. Most research on retinal degeneration has focused on the ciliated photoreceptor ce...
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| Principais autores: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2023-12-01
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| Serier: | PLoS Biology |
| Online adgang: | https://doi.org/10.1371/journal.pbio.3002402 |
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