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An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

The retinal pigment epithelium (RPE) provides vital metabolic support for retinal photoreceptor cells and is an important player in numerous retinal diseases. Gene manipulation in mice using the Cre-LoxP system is an invaluable tool for studying the genetic basis of these retinal diseases. However,...

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Principais autores: Elliot H. Choi, Susie Suh, David E. Einstein, Henri Leinonen, Zhiqian Dong, Sriganesh Ramachandra Rao, Steven J. Fliesler, Seth Blackshaw, Minzhong Yu, Neal S. Peachey, Krzysztof Palczewski, Philip D. Kiser
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2021-05-01
Serier:JCI Insight
Fag:
Genetics
Ophthalmology
Online adgang:https://doi.org/10.1172/jci.insight.146604
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