Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.

Vision impairment places a serious burden on the aging society, affecting the lives of millions of people. Many retinal diseases are of genetic origin, of which over 50% are due to mutations in cilia-associated genes. Most research on retinal degeneration has focused on the ciliated photoreceptor ce...

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Hlavní autoři:	Viola Kretschmer, Sandra Schneider, Peter Andreas Matthiessen, Dominik Reichert, Nathan Hotaling, Gunnar Glasßer, Ingo Lieberwirth, Kapil Bharti, Rossella De Cegli, Ivan Conte, Emeline F Nandrot, Helen Louise May-Simera
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2023-12-01
Edice:	PLoS Biology
On-line přístup:	https://doi.org/10.1371/journal.pbio.3002402
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