Ethylenediaminetetraacetic Acid (EDTA)-Decalcified, Formalin-Fixed Paraffin-Embedded (FFPE) Tumor Tissue Shows Comparable Quality and Quantity of DNA to Non-Decalcified Tissue in Next-Generation Sequencing (NGS)

<b>Background:</b> Bone tissue decalcification is essential for histopathological evaluation, but conventional methods using inorganic acids degrade nucleic acids, limiting molecular testing. EDTA is known to better preserve DNA, but its suitability for next-generation sequencing (NGS) in clinical s...

Повний опис

Бібліографічні деталі

Автори:	Francis Hong Xin Yap, Jen-Hwei Sng, Jeremy Wee Kiat Ng, Hanis Abdul Kadir, Pei Yi Chan, Timothy Kwang Yong Tay
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2025-09-01
Серія:	Journal of Molecular Pathology
Предмети:	Ethylenediaminetetraacetic Acid (EDTA) next-generation sequencing (NGS) decalcification
Онлайн доступ:	https://www.mdpi.com/2673-5261/6/3/21
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!