Synthesis and biological evaluation of novel 1,2,3-triazole hybrids of cabotegravir: identification of potent antitumor activity against lung cancer

In pursuit of discovering novel anticancer agents, we designed and synthesized a series of novel 1,2,3-triazole hybrids based on cabotegravir analogues. These compounds were subjected to initial biological evaluations to assess their anticancer activities against non-small-cell lung cancer (NSCLC)....

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Bibliografische Detailangaben

Hauptverfasser:	Yajie Guo, Dan Sang, Bin Guo, Dan Wang, Xinyue Xu, Huili Wang, Cuilan Hou, Longfei Mao, Fang Li, Sanqiang Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-09-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	1,2,3-triazoles cabotegravir anticancer lung cancer apoptosis ROS
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1265245/full
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