Synthesis of compounds based on the active domain of cabotegravir and their application in inhibiting tumor cells activity
Abstract Structural modification based on existing drugs, which ensures the safety of marketed drugs, is an essential approach in developing new drugs. In this study, we modified the structure of cabotegravir by introducing the front alkyne on the core structure through chemical reaction, resulting...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley-VCH
2024-07-01
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| coleção: | ChemistryOpen |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/open.202300284 |
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