XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation
X-linked inhibitor of apoptosis protein (XIAP) has been identified as a potent regulator of innate immune responses, and loss-of-function mutations in XIAP cause the development of the X-linked lymphoproliferative syndrome type 2 (XLP-2) in humans. Using gene-targeted mice, we show that loss of XIAP...
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| Hlavní autoři: | , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2014-06-01
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| Edice: | Cell Reports |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2211124714003830 |
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