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Induction and redistribution of XAF1, a new antagonist of XIAP in the rat brain after transient focal ischemia

Apoptotic cell death occurs in neurons after cerebral ischemia. To investigate the molecular basis of this mechanism of cell death, we explored the expression and localization of Smac/DIABLO, a newly identified mitochondrial apoptogenic molecule, and XAF1, a recently identified antagonist of XIAP an...

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Glavni autori: M. Siegelin, O. Touzani, J. Toutain, P. Liston, A. Rami
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2005-11-01
Serija:Neurobiology of Disease
Teme:
Apoptosis
Focal ischemia
XAF1
XIAP
Caspase
Smac/DIABLO
Online pristup:http://www.sciencedirect.com/science/article/pii/S0969996105001245
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