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Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain

Abstract Background The role of the innate immune system in Alzheimer’s disease (AD) and neurodegenerative disease susceptibility has recently been highlighted in genetic studies. However, we do not know whether risk for inflammatory disease predisposes unaffected individuals to late-life cognitive...

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主要な著者: Daniel Felsky, Ellis Patrick, Julie A. Schneider, Sara Mostafavi, Chris Gaiteri, Nikolaos Patsopoulos, David A. Bennett, Philip L. De Jager
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2018-07-01
シリーズ:Molecular Neurodegeneration
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オンライン・アクセス:http://link.springer.com/article/10.1186/s13024-018-0272-6
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